Vitamin B9 (Folate)
Vitamin B9 (Folate)
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Indications
Both Vitamin B9 (folate) and Vitamin B12 present diagnostic challenges due to overlapping deficiency symptoms, which may require additional tests for accurate diagnosis. Elevated P-Homocysteine levels can indicate folate deficiency but also appear in cases of cobalamin (Vitamin B12) deficiency. However, an increase in serum methylmalonic acid (MMA) is only seen in cobalamin deficiency and remains unaffected by folate levels. A significant number of patients with folate deficiency may have a genetically inherited functional deficiency due to the presence of the C667T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene, which reduces enzyme function.
Additional Information
Folate is a nutrient found in small amounts in almost all foods. It is essential for the production of red blood cells and the creation of new cells. During periods of increased cell production, such as pregnancy or growth, the need for folate rises. Folate is also known as folic acid; however, these are two forms of the same B-vitamin. Folate is naturally obtained through diet, while folic acid, the synthetic form, can be supplemented through fortified foods and dietary supplements if needed.
The folate test is recommended if you experience the following symptoms:
• Fatigue and exhaustion
• Mucosal issues and mouth sores
• Hair loss
• Difficulty with concentration and memory
• Muscle and joint pain
• Slow-healing wounds
Additionally, it is crucial to test folate levels if you are pregnant, planning a pregnancy, or following a diet low in folate.
